Scientists Identify Gene Linked to Enlarged Heart

From Health Day News:

A new genetic cause of enlarged heart has been identified by an international team of scientists, who said their finding could lead to new treatments.

In research with rodents and humans, the scientists found that the gene osteoglycin (Ogn) regulates the growth of the heart's left ventricle, it's main pumping chamber. When Ogn behaves abnormally, the heart can become enlarged, BBC News reported.

The study appears in the journal Nature Genetics.

It was already known that irregular heart growth can be caused by obesity, high blood pressure and strenuous exercise, but the influence of genes is largely unknown, BBC News reported.

"But, now that we are unraveling how genes control heart growth, we can gain a better understanding of common forms of heart disease. This could lead to new and more effective ways of treating people," said researcher Dr. Stuart Cook.